More Information
Neurology News
Neurology Clinical Trials
Ways to Give
Web Rounds

 

Neurology

Education and Training

Neurology Fellowship Programs

Experimental Therapeutics of Neurological Disorders

Important Programs and Facilities

Translational Neurology at the Bench

Translational Research
A joint initiative of the Departments of Neurology and Neurosurgery is the new URMC Center for Translational Neuromedicine. The Center includes the Divisions of Cell and Gene Therapy of the Neurology Department, and of Glial Diseases and Therapeutics of the Department of Neurosurgery, Co-directed by Steven Goldman, M.D., Ph.D. and Maiken Nedergaard, M.D., DMSc. The Center is exploiting neuronal and glial progenitor cells to develop new treatments for a variety of diseases including the neurodegenerative diseases, myelin diseases, and CNS tumors.

Translational Neurology: Bench to Bedside

Clinical Trial Design
Experimental Therapeutics Unit (a collaborative program of Pharmacology and Physiology, Neurology, Psychiatry, Biostatistics and other departments) under the leadership of Ira Shoulson, M.D., Louis C. Lasagna Professor in Experimental Therapeutics.

Clinical Coordination and Execution
The Department including the Headquarters for Coordinating Centers for multi-center therapeutic trials in a variety of neurological diseases.  They include: Parkinson's disease, Huntington's disease, Tourette’s syndrome, dystonia, Alzheimer's disease, multiple sclerosis, epilepsy, peripheral neuropathy, Duchenne dystrophy, facioscapulohumeral dystrophy, inclusion body myositis, myotonic dystrophy, periodic paralysis, episodic ataxia, AIDS, dementia and attention deficit disorder. Many of these studies are coordinated through a free standing entity, the Clinical Trials Coordination Center (CTCC) directed by Karl Kieburtz, M.D., MPH.

Clinical Research Center
Neurology has major involvement in the NIH-funded Clinical Research Center of the University of Rochester. This facility accommodates both inpatient and outpatient clinical studies and is a part of Rochester’s Clinical and Translational Science Institute, of which Rochester is one of 38 NIH funded sites nationally.  Richard T. Moxley, III, M.D. is Associate Director of the Clinical Research Center. 

Translational Neurology: At the Bedside

Movement Disorders
Movement and Inherited Neurologic Disorders (MIND): working in concert with the Clinical Trials Coordination Center, the MIND Unit trains fellows in the clinical and experimental evaluation of movement disorders.  Fellows are also trained in surgical management and deep brain stimulation, working together with colleagues in the Department of Neurosurgery.  The MIND Unit is directed by Bernard Ravina, MD, MSCE.

Epilepsy
Strong Epilepsy Program at the University of Rochester Medical Center:  Funded by New York State, federal and private support, this program brings state-of-the-art medical and surgical treatment to patients with epilepsy.  Rochester is the coordinating center for a multi-center clinical trial assessing the effectiveness of early surgery for intractable epilepsy.

Neuromuscular Disease
Center grants funded by NINDS (2003-2008):  Muscular Dystrophy Cooperative Research Center, Principal Investigator: Richard T. Moxley, III, M.D.; Clinical Investigation of Neurological Channelopathies, Principal Investigator:  Robert C. Griggs, M.D.

The Muscle Study Group (MSG) Coordination Center is directed by Rabi Tawil, M.D. These provide the facilities and support for the conduct of major multi-center clinical trials, sponsored by NIH, FDA, many foundations and the pharmaceutical industry.

Translational Neurology:  Design and Assessment

Health Services Delivery
Major programs in health services research with faculty who maintain joint appointments in the Department of Community and Preventive Medicine, directed by Robert G. Holloway, M.D., M.P.H., Professor of Neurology.

Epidemiology and Statistics
Major interactions with the Department of Biostatistics and Computational Biology including full-time joint faculty appointments, (Michael McDermott, Ph.D. and Christopher Beck, Ph.D.) and major computer and programming resources.