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Urology Clinical Trials

 

Urology

Research

Urology Clinical Trials

Past Urology Trials in Bladder Conditions and Bladder Cancer

  • A study of an investigational drug, resiniferatoxin (RTX), for the treatment of symptoms associated with an overactive bladder in subjects with disease or injury of the nervous system.

  • The major purpose of this research study is to determine the effectiveness of standard Bacillus Calmete-Guerin (BCG) immune therapy for bladder cancer can be improved by the addition of another immune-stimulating drug interferon-alpha. BCG alone has been shown to be the most effective treatment for superficial bladder cancer with roughly 2/3 to 3/4 of patients responding. BCG is approved for use in aggressive forms of this disease.

  • A study to evaluate the use of a tumor marker, NMP22, as an aid in screening for bladder cancer in urine in subjects with risk and symptoms but no previous history of urinary tract cancer.

    A study to evaluate the use of a tumor marker, NMP22, as an aid in monitoring bladder cancer in subjects with urinary tract cancer.

  • A study to evaluate a test aimed at early detection of bladder cancer. Changes have been detected in urine of patients diagnosed with bladder cancer. This experimental test looks for the presence of abnormal genes in cells taken from urine.

  • A study to determine the ability of a new laboratory test (P53 Mutation Test) to predict the likelihood of bladder cancer recurring or progressing based on the analysis of a single voided urine specimen. In addition, it will compare this test with other available tests and procedures used to predict recurrence and progression of bladder cancer. The p53 Mutation Test is a genetic test that looks for changes in the P53 gene in the urine specimen.

  • A research study to determine whether or not the UroVysion test can be used for early detection of bladder cancer in subjects who have not previously been diagnosed with bladder cancer, but who may be experiencing symptoms associated with bladder cancer. The UroVysion test is investigational for early detection of bladder cancer.

  • A research study to determine the PathVysion Bladder Test as an investigational urine test for bladder cancer. It is hoped that your participation in this study will further the knowledge and understanding of whether or not these tests will help in bladder cancer monitoring and management.